| 產品名稱 |
Avian coronavirus |
| 商品貨號 |
B162911 |
| Classification |
Coronaviridae, Gammacoronavirus |
| Agent |
Avian coronavirus |
| Strain |
M41 |
| Common Name |
Infectious bronchitis virus (IBV) |
| Applications |
Unlike fully egg-adapted strains that are non-immunogenic, this strain produces satisfactory immunity as determined by neutralization test for antibodies. |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format |
frozen |
| Storage Conditions |
?-70°C or colder |
| Comments |
The M41 (Massachusetts [Michigan State University Repository Code 41]) strain is the protype strain of IBV, however it should be noted that antigenicity and virulence of IBV change readily with passage in culture. Unlike fully egg-adapted strains that are non-immunogenic, this strain produces satisfactory immunity as determined by neutralization test for antibodies. |
| Effect on Host |
Yes, in vivo effects: curling, stunting and pale coloring of infected embryos or chickens; may cause death. |
| Recommended Host |
Production Host: Embryonated chicken egg (9 to 10-day old). Recommended Host: ?Embryonated chicken egg (9 to 10 day old) Alternate Host: Chicken (10-day old, intratracheal inoculation). |
| Growth Conditions |
Temperature: 37.0°C Recommendations for Infection: Inoculate embryonated chicken eggs (9 to 10-day old) by the allantoic cavity route with 0.2 mL of a 1:10 to 1:100 dilution of virus in DPBS. Incubation: 2-6 days |
| Name of Depositor |
CH Cunningham, Michigan State University |
| Special Collection |
ATCC |
| Chain of Custody |
Deposited as Infectious bronchitis virus |
| Source |
Isolated in 1941 from 19-day old chicks accidentally infected in the laboratory, University of Massachusetts. |
| References |
Cunningham CH. Symposium on immunization against infectious bronchitis virus. I. Some basic properties of infectious bronchitis virus. Am. J. Vet. Res. 18: 648, 1957. PubMed: 13444588
Cunningham CH. . Adv. Vet. Sci. 14: 106-148, 1970.
McIntosh K. . Curr. Top. Microbiol. Immunol. 63: 86-119, 1974.
Cunningham CH. . Am. J. Vet. Res. 21: 498, 1960.
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